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As shown in Figure 1(b), another two survival-associated subnetworks have been associated with cell death module.
As shown in Figure 1(a), two survival-associated subnetworks have been associated with cell death module.
Therefore, both extracellular matrix and cell death module, the two master themes identified in our network analysis, were reproduced from GO analysis.
Over 400 ovarian cancer expression arrays have been analyzed, and extracellular matrix and cell death module were regarded as the main themes associated with ovarian survival data.
Specifically, we showed that CCR and their ligands may contribute to cancer progression in part via the FBLN2-BAT3 branch of the cell death module).
The GSEA analysis was used to discover miRNAs that significantly regulate the two modules the extracellular matrix module (ECM) and the cell death module (CDM).
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One of Delrina's screensaver products was based on the licensed Bloom County characters Opus the Penguin and Bill the Cat. The initial Opus 'n Bill screensaver, launched in 1993, landed the company in court as its Death Toasters module depicted Opus taking shots at a number of flying toasters, a well-known emblem in Berkeley System's Flying Toasters module from their After Dark screensaver.
Therefore, the cell death signaling module can be a novel network-based biomarker of ovarian cancer.
While in the advanced stage of the ovarian cancer, the dysfunctional cell death signaling module will facilitate the ovarian cancer progression.
An exception is the het-s/het-S incompatibility system which does not involve a HET domain as cell death execution module.
In the early stage of the ovarian cancer, the cell death signaling module can restrict cell proliferation by regulating apoptosis and autophagy.
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