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Then we also confirmed the protection of Rapa from thapsigargin (Tg -induced cell deaTg -inducedry hepatocells.
Concentrations up to 8% did not elicit cell death in primary rat astrocytes or neurons at 1 or 7 days.
Moreover, poly I C never induced direct hepatocyte death in primary culture whatever the murine genotype, while it always stimulated an anti-viral response.
Chloroquine-induced cell death in primary MEFs and human colorectal cancer cells was dependent upon p53, but not upon the p53 modulators Atm or Arf.
The leading cause of death in primary and secondary APS patients are cardiovascular events due to accelerated atherosclerosis, which often progresses more rapidly, compared with the general population [14].
These findings demonstrate the complex nature of cell death in primary cells of the retina and highlight the role of caspase-independent signals, growth factors and intracellular survival factors in programmed cell death pathways.
Cell viability assays showed that EA selectively induced cell death in primary CLL cells.
We analyzed the characteristics of cell death in primary murine macrophages challenged with virulent or attenuated M. tuberculosis complex strains.
We first determined the effect of the O2.− generating compound PQ2+ on aconitase activity, H2O2 production, mitochondrial Fe2+ accumulation and cell death in primary midbrain cultures.
Like in cancer cells arrested by Plk1 depletion or inhibition, we also observed cell death in primary cells following the mitotic arrest.
The IKKβ-inhibitor also prevented cytokine induced loss of insulin production and beta cell death in primary islets and beta cells, possibly by inhibition of ROS production.
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