Subsequently, one study reported that 131I-labeled B-B4 mAb induced cellular death in an in vitro multiple myeloma model [15].
We estimated the hazard ratios for breast cancer specific death using Cox regression implemented in a multiple imputation framework to deal with missing data on stage and grade (Table 3).
Both human multiple myeloma cell lines were sensitive to intracellular elevation of cAMP, indicating that elevation of intracellular levels of cAMP indeed also induces cell death in human multiple myeloma cells.
Hastings' death in a Los Angeles car crash has sparked multiple conspiracy theories, most of which center around the idea that Hastings was sabotaged in some way because he often reported on sensitive national security topics.
More recently, we demonstrated that fisetin was effective at slowing death in multiple models of Huntington's disease in a partially ERK-dependent manner (Maher et al., 2011).
Chaudry and Zellweger were examining the mechanism by which sepsis produces multiple organ failure and death in a murine model.
Trish Chelsen, whose husband, Roy, was a New York City firefighter, said she believed his death in January of multiple myeloma was caused by the chemicals at ground zero.
Deletion of Ddit3, the gene encoding CHOP, has also been reported to reduce cell death in multiple tissues in several disease mouse models associated with ER stress including a neurotoxin-induced Parkinson disease model, the demyelinating Charcot Marie Tooth 1B mouse model, and a model of diabetes (36– 36).
Caspase-3 dependency of PAC-1-induced cell death was supported by the data of cell death in multiple normal and cancer cell lines that strongly placed caspase-3 expression as a deciding factor for its cytotoxicity.. So, in order to further validate the caspase-3 dependency, we compared cell death in the presence (MCFC3) and absence of caspase-3 (MCF7).
In a 2006 interview, J. K. Rowling said that the main theme of the series is Harry dealing with death, which was influenced by her mother's death in 1990, from multiple sclerosis.
