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The synergy scores are heavily weighted for cell death effects by the combined compounds to allow more effective ranking of the combination.
The cells treated with TANG were significantly increased cell growth suppression and cell death effects than vehicle treated cells.
Non-apoptotic-related cell death effects were not seen in the current data, which indicates that apoptosis was the main process involved in the reduction of tumor volume.
Thus, HO-1 and CO oppose multiple proinflammatory and pro-cell death effects of IL-18 in human microvascular endothelial cells.
These findings indicate that the pro-cell death effects of TG2 are dependent on its localization to the cytosol and independent of its transamidation activity.
In addition to anti-cell death effects, these kinases are also involved in the antagonizing effect of HN against amnesia caused by muscarinic receptor blockade in vivo [23].
Similar(36)
Yet clubs who have this kiss of death effect can hardly be expected to celebrate the matter – they are usually too busy worrying about their own prospects of survival.
"Paid leave actually has a life [or] death effect," she wrote.
Some killings surpass brutality: 41 elephants were poisoned with cyanide at a Zimbabwe national park, creating a fourth-generation death effect -- animals feeding on the elephant carcasses die from the poisoning, then other animals feeding on them also die.
This death effect requires the presence of a short C-terminal domain containing the conserved mitochondrial death sequence 71-HFRIGCRHSRIG-82 71-HFRIGCRHSRIG-82 71-HFRIGCRHSRIG-82
We next wished to study whether the cell death effect of SecTRAPs required induction of novel protein synthesis.
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