TRAIL induces apoptosis in various cancer cells through its interaction with death receptor 5 (DR5), which contains a cytoplasmic death domain capable of recruiting apoptosis signaling molecules and inducing apoptosis [ 15- 21].
While Americans reasonably could, and often did, conclude that fascism had become an existential threat to American democracy, the Islamic State — a death cult capable of enormous acts of evil, to be sure — hardly poses a similar such total threat to the world's strongest military and economic power.
Surely death is capable of benefitting us the same way that anesthetization and unconsciousness can.
Therefore, apoptosis and necrosis have been assumed to be two extremes of the cell death spectrum capable of inter-conversion by key regulators.
A separate approach to limit off-target damage caused by CAR+ T cells involves the co-expression of a death switch capable of rapidly shutting down the CAR+ T-cell effector response.
In the absence of cellular injury and death, proteases capable of degrading endostatin are reduced and local levels of endostatin begin to rise again, restoring the balance between pro- and antiangiogenic factors.
Although the presence of activated microglia following the onset of cell death is a well-accepted notion, the fact that microglia is activated early in α-syn models and in patients suggests that α-syn-related events involved in the neurodegenerative process that occurs prior to cell death are capable of activating the microglia.
PRO-Pep4p protected cells from hydrogen peroxide-induced cell death and was capable of retarding the onset of death in the Δ pep4 mutant (Supplementary Figure S4C).
Like Odin, the Christian god commanded a heavenly host, promised his followers rewards after death and was capable of prodigious feats of slaughter.
It looks like this:Mr Burns confesses he's "not sure" this is actually called a debrainer, but he is sure that "in the right hands, this implement of death is quite capable of extracting a brain".
