Its death-inducing capability is often masked by the anti-apoptotic effects of NF-κB (Gaur and Aggarwal, 2003).
Being an important regulator of Golgi architecture and membrane trafficking, we initially predicted that GRASP65 cleavage would alter Fas/CD95 trafficking through the secretory and/or endocytic pathways, thereby affecting the cell-death-inducing capability of the Fas/CD95 population.
Ortiz's attorney and others said the problems in his case weren't much different than those that bedevil many of the other 62 people still on federal death row impaired mental capability, substandard trial lawyers, and geographic and racial disparities.
Nominations for a Darwin Award are evaluated according to five rigorous selection criteria: death, style, veracity, capability, and self selection.
Previous investigators have documented the sensitivity of various MM cell lines to TRAIL-induced cell death, and the capability of HDACi to synergize with rhTRAIL through mechanisms including reactivation of silenced caspase-8, downregulation of c-FLIP and restoration of cell surface DR-4/5 expression.
However, in situations where ROS production exceeds the cell's antioxidant capability, cell death can occur by interfering with normal physiological processes and the modification of cellular biomolecules [28].
Today military action would be a wild gamble because the North possesses the conventional capability to rain death and destruction down upon Seoul, South Korea's capital.
The genetic changes produce phenotypic changes associated with increased proliferation capabilities, decreased death, enhanced migration and invasion, evasion of the immune system, or the ability to induce angiogenesis.
Altogether, as only hypomorphic mutations are present in males, it seems that more severe mutations, such as the p. (Val107Phe) variant, in hemizygous state might lead to an early intrauterine fetal death, which escapes analytical capabilities.
Postnatal ∆9 Lmna fibroblasts (MAFs), established from several different tissues, show a highly restricted proliferative capability with early death.
In a study involving α-radiation exposure of cells, the probability of cell death or loss of reproductive capability was 66% per α-traversal of the cell 1.
