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There was death, breakage, abandonment, unwelcome people showing up at the front door with all manner of unwelcome news.
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"Death and breakage is part of the system".
PM10 from all three zones of Mexico City caused cell death, DNA breakage, and apoptosis, with particles from the north and central zones being the most toxic.
Entry or activation of an epigenetic DNA methylation system also causes cell death through chromosomal breakage by methyl-DNA-specific DNases that lead to elimination of cells with an altered epigenome.
Thus, skeletal trauma analysis differentiates between patterns of violent trauma caused by a weapon at the time of death and fracturing or breakage caused by animals or weathering after death.
Here, we found that inhibition of the kinase ATR, which is the primary sensor of DNA replication stress, induced chromosomal breakage and death of mouse AMLMLL cells (with an MLL-ENL fusion and a constitutively active N-RAS) independently of p53.
Such events do not necessarily lead to DNA breakage and cell death.
Atrophic and broken ETC‐abnormal fibers were consistently positive for apoptosis and necrosis, indicating that cell death pathway activation mediates fiber breakage and loss.
The positive effect of MUS81 on RF restart seen in mouse cells could not be discerned in U2OS cells treated with siRNA against MUS81 after prolonged HU treatment (Petermann et al. 2010), and extensive treatment periods (36 h) have been shown to lead to massive MUS81-induced DNA breakage and cell death (Fugger et al. 2013).
Some cells will lose the last copy of the plasmid and suffer further chromosomal restriction breakage and consequent cell death.
It has been blamed for about 300 deaths that resulted from the breakage of a metal wire that makes a disk inside the valve open and close.
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CEO of Professional Science Editing for Scientists @ prosciediting.com