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In failing heart apoptotic and autophagic cell death are increased.
Risk for illness and death are increased for these patients.
Cardiac disease and sudden cardiac death are increased in patients undergoing dialysis [ 74, 75].
Flow-mediated vasodilation is decreased, whereas endothelial microparticles, indicators of endothelial cell death, are increased.
Our findings suggest that the risks of readmission to hospital and death are increased well beyond the initial month after hospital discharge.
It is noteworthy that apoptotic proteins levels and cell death are increased in adipocytes of obese humans and rodents, and genetic depletion of the pro-apoptotic BH3-only protein Bid protects from liver steatosis and insulin resistance in high fat diet regimes [ 83].
Similar(54)
Mortality among infected patients was 38.1 %, and the risk of death was increased as patients were infected (p < 0.001, 95 % CI [1.782 4.021], OR 3.784).
Finally, cell death was increased significantly by UbV.7.2 expression in a colon cancer cell line that was treated with the chemotherapy drug cisplatin, demonstrating the therapeutic potential of inhibiting USP7 by this approach.
Cell death was increased with time.
The mean time to death was increased by almost 1 day (Figure 9A).
In line with this observation, cell death was increased in mycoplasma-contaminated LNC cultures (Figure S1B).
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