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Deactivation time of the catalyst is highly dependent on the contact time, doubling the feed rate decreased the deactivation time by a factor of 10 and lowered the olefin production.
Simulation results show that the performance of the proposed controller is better compared to the controller ignoring the catalyst deactivation when the deactivation time is close to the resident time of the reactor.
Independently of the value of n, a cross —effect is attained consisting in a higher average conversion in the catalyst bed of higher internal diffusion resistance at a sufficiently long deactivation time.
The mean deactivation time constant (tau) was determined by fitting the current at the applied test potentials with a single exponential.
Application of 100 µM 5-chloroindole also slowed the deactivation time constant from 3.6±0.5 ms to 6.3±1.2 ms, N = 3 (Fig. 6C).
The benzofurans did not affect channel function, they did not shift the conductance versus voltage relationship or slow the deactivation time course.
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Since propofol alters the deactivation time-scale of GABAa receptor channels, we consider τ s as our main study parameter.
This gives access to information on catalyst activity, activation and deactivation times of the catalyst, polymerization kinetics, copolymerization parameters, and the degree of homogeneity of the resulting copolymers.
Both activation and deactivation time-courses were accelerated for L532P IhERG.
The deactivation time-course for WT and N588K IhERG1a/1b was, however, faster than that of the corresponding hERG1a channels (data not shown), consistent with accelerated deactivation reported previously for WT hERG1a/1b [16,18,20].
The lack of a resurgent IhERG tail and extremely rapid deactivation time-course for WT IhERG1b indicates that, concordant with previous evidence [17,18], WT IhERG1b expressed alone does not recapitulate native IKr; therefore all further experiments were conducted using co-expressed hERG1a/1b.
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