In this approach, the goal is to specifically deactivate CDK4/6 function in Rb phosphorylation since the catalytic activity of these kinases regulates the checkpoint for the G1/S transition and the commitment to cell division [reviewed in Bloom and Cross (2007), Ekholm and Reed (2000), Hochegger et al. (2008), Morgan (1997)].
IL-10 deactivates macrophage function [ 170] by downregulating IL-12 and TNF α expression, which in turn reduces production of IFN γ by T cells and thus aids in Mtb survival.
A regulatory pathway begins with a causal gene and ends at a target gene, and each gene in a pathway can either activate or deactivate some functions of its neighboring genes.
The metal function deactivated faster than the acid function, though it was not significantly severe to cause a drop in n-C7 conversion.
Furthermore, in all the three catalysts, the metal function deactivated faster than the acid function; however, this was not severe enough to cause a drop in the n-C7 conversion.
The metal function deactivated faster than the acid function in all the composite catalysts but did not cause a severe drop in n-C7 conversion, indicating that the composite zeolite pore structure plays a very important role in the conversion, and an appropriate combination of the pore structure and acidity showed superior TOS behaviour.
Heterochromatinization progresses with aging and can deactivate many previously functioning active genes.
Steroidal hormones are usually deactivated after their function is complete in the liver using biochemical transformations that modify chemically its structure.
In practice, some sensors of aircraft engines naturally fail to obtain an acceptable measurement for control propose, which will severely degrade the system performance and even deactivate the limit protection function.
The analysis of the set of root genes responding to the soil effect shows that 132 gene sets (see Additional file 1: Table S3) play a role by activating or deactivating several root functions, depending on the soil composition.
Under the law, drivers will be allowed to touch their phones to activate or deactivate the hands-free functions.
