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There was no significant difference in ORR, but significant better DCR in patients with low HGF compared with those with high HGF (DCR: 78.6 vs 57.4%, P=0.021).
Regarding efficacy, despite the fact that PMs received smaller doses of tivantinib than EMs, DCR in PMs in this study (55.5%) was not remarkably different from both DCRs in EMs in this study (50.0%) or in comparison with the phase II Western clinical trial (ARQ 197-209, 64.4% Sequist et al, 2011).
DCR in the trial of regorafenib and TAS102 were 41 and 43.8 %, while the DCR of BSC group in these trials were 15 and 10.5 %, respectively [ 15, 16].
Yet fifteen years later, it's still the only Drug Consumption Room (DCR) in the country.
The purpose of this study was to evaluate outcomes between nonlaser endonasal endoscopic and external dacryocystorhinostomy (DCR) in a district general hospital in the United Kingdom.
So HCR outperforms DARA and DCR in terms of travel distance in a motion.
Similar(18)
Down-regulation of the DcRs in cancer renders cancer cells more susceptible to TRAIL-induced apoptosis, which could be counted as a protective response against tumor formation or progression.
Fenretinide induced rapid upregulation of both DcRs in all ESFT cells.
However, the DCRs in current study and the Caucasian phase II study were 31 and 63% respectively (Glazer et al, 2010).
After irradiation ceased, actual DCRs slightly improved due to spontaneous annealing, leading to an apparent DCR rise in the over-saturated samples.
The DCR increase in each device followed the radiation dose applied, conditional that operating temperatures were kept sufficiently low - at high temperatures, the device count rates saturated.
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