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Here, we demonstrate, for the first time, that IFN-α-conditioned monocyte-derived DC act as highly efficient APC in inducing autologous IL-17-secreting Th17 cells, and that this effect is mediated by IL-23 and IL-12, as clearly indicated by the results of the neutralization experiments (Fig. 6).
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As the same manner, the difference of compressive resultant dC acts on the upper face.
This week, the federal appeals court in DC acted, by a 9-2 voto, to slap down Pruitt's unlawful effort to suspend an EPA rule governing methane emissions from oil and gas companies pending an effort to revisit the rule.
The results found in the analysis of disease progression markers over time further support that a higher production of α-defensins1-3 by immature DC acts as a protective host factor against disease progression.
Since the DC acts as the most potent APC, we have previously used siRNA to manipulate expression of immunological genes in antigen pulsed DCs to either upregulate or suppress immune responses in a specific manner [ 9, 10].
DC acted as an Advisory Board member of Merck-Serono, Teva, Bayer Schering, Biogen Idec, Novartis, Almirall and GW Pharmaceuticals and received funding for travelling and honoraria for speaking or consultation fees from Merck-Serono, Teva, Novartis, Bayer Schering, Sanofi-aventis, Biogen Idec and Almirall.
Dendritic cells (DCs) act as a portal for virus invasion and as the most potent antigen-presenting cells in antiviral host defense.
Dendritic cells (DCs) act as a first-line recognition system for invading pathogens, such as influenza A. The interaction of DC with influenza A virus results in DC activation via endosomal Toll-like receptors and also leads to presentation of viral peptides on MHC class II molecules.
Dendritic cells (DCs) act as a link between innate and adaptive immunity and originate from both myeloid and lymphoid progenitor cells [15].
In vivo, the DCs act as a scaffold supporting outer hair cells (OHCs) standing on the basilar membrane [5].
DCs act as a bridge between the innate and the adaptive immune responses by sensing pathogens through PRRs and inducing adaptive immune responses [7], [8], [20], [21].
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