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We focus on embryonic day 11.5 (E11.5), which is equivalent to roughly 40 days of gestation in human.
We included singleton pregnancies with gestational ages between 37 weeks +0 days (259 days of gestation) and 43 weeks + 6 days (307 days of gestation), thus excluding preterm births.
Lambs were delivered at 125 days of gestation (preterm) or 145 days of gestation (term).
Necrotic tips became apparent after 27 days of gestation.
At 30 days of gestation, a second-look laparotomy was performed.
The greatest increase in placenta weight occurred between 37 and 42 days of gestation.
Litter size, 12.1 ± 3.4, was similar for all days of gestation.
Study design: Pregnant ewes were chosen randomly to receive saline solution, one dose of 0.5 mg/kg betamethasone at 104 days of gestation, or three doses of 0.5 mg/kg betamethasone at 104, 111, and 118 days of gestation.
Conclusion: Medical abortion between 64 and 91 days of gestation is effective and has a high uptake.
Study Design: Pregnant sheep were randomized to receive MPA or saline solution at 100 days of gestation.
The feeding trial lasted for 51 days, including 30 days of gestation and 21 days of lactation.
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