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DFS was defined as the period starting from the day of enrollment and ending on the day of recurrence; the day a cancerous, non-recurrent lesion (either synchronous or metachronous) was detected for the first time after the day of enrollment; or the day of death from any cause, whichever was earlier.
The mean parasite density at day of recurrence was very low (GM = 41.1/μl; interquartile range [IQR], 23.3 to 855.8).
Disease-free survival was considered from the day of surgery to the day of recurrence or censored at most recent follow-up.
Dried blood samples for measuring CQ blood concentrations were available (at day 7 and the day of recurrence) for 5 of the 8 patients with vivax malaria recurrence, and among these, three had interpretable results.
If, for any of the six loci, an allele was not shared between day 0 and day of recurrence, the infection was classified as a new infection.
Pfmdr-1 and Pfcrt genes were amplified in samples from enrolment (and day of recurrence in cases of CQ treatment failure) by nested PCR approach, as described [12].
Similar(42)
Disease-free survival was defined as the time between the day of surgery and day of recurrent disease, and post-recurrence survival was defined as the time between the first recurrence and death or last follow-up.
A small (n = 20), but well controlled (randomized, double-blind, placebo-controlled case control) study [ 17] in which the effect of 1200 mg lysine per day on recurrence, duration and severity of herpetic lesions was investigated for 4 5 months, confirmed the negative findings of Milman et al. [ 20, 21].
One milliliter of blood was obtained from all patients on day 0 and on the day of the recurrence as evidenced by microscopy.
Fresh urine samples were collected in the morning one day prior to surgery (Preop-1d urine) [ 9, 16], the day after surgery (Postop-1d urine), one week after surgery (Postop-1w urine), and on the day of tumor recurrence diagnosis (Post- r urine).
Disease-free survival was defined from the operation day to the identification date of recurrence of cancer or death from any cause, and overall survival was defined from the operation day to death from any cause.
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