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The 13-item depression scale and the 10-item anxiety scale of the revised Hopkins Symptom CheckList (SCL-90-R) were used, in order to measure psychological symptom status with a time reference of the past 7 days, including the day of assessment.
In the deterministic analyses, the number of days of treatment and day of assessment of adverse effects occurring with first- or second-line treatment were modified (Table 1), as well as different doses and schedules for micafungin and caspofungin (according to different body weights and other factors).
Survival in days was measured from the day of assessment.
Thereafter participants will reconstruct victimization in the past 90 days, following the same procedure, beginning on the day of assessment and working backwards.
Complete assessment was not possible in three children; one child could not be encouraged to participate and was later diagnosed with an autistic spectrum disorder, complete testing equipment was not available on the day of assessment for another child, and one child was assessed using the mental and cognitive items only because of time restrictions.
This represents a compromise between assessing disease activity based on clinical features on day of assessment, which may be unrepresentative of overall disease activity and clinical features present over a longer time period, as in the IBDDAM, which reduces reliability in terms of accurate recall of symptoms by patients.
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Eight students were absent on the day of assessments and did not participate.
Prolonged and successful weaning were defined as dependance on MV for ≥ 7 and < 7 days respectively from the day of weaning assessment.
Nonetheless, these remaining levels of nuclear EpICD were instrumental for the rapid induction of target genes, which reached a plateau at day two of assessment.
Patients and their caregivers were introduced to the assessments in the waiting area on the day of the assessment and asked to provide verbal informed assent/consent at the beginning of the consultation.
Participants were advised to abstain from caffeinated food and beverages on the day of the assessment and avoid exercise for at least 24 hours prior to the assessment.
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