Exact(1)
All patients will be given as much time as they require and offered separate alternative day enrolment appointments (see online supplementary files for model copy of the trial consent form).
Similar(59)
All patients will be contacted by person at day of enrolment, 3 4 days and 28 32 days thereafter and are contacted by phone at 13 15 days and 84 92 days after enrolment to assess outcome.
They were also asked to submit to a telephone follow-up interview to be conducted as soon as practicable after three days from the day of enrolment.
All patients were tested with the ICT-TB on the day of enrolment or not later than 3 days after enrolment.
Five ml blood were collected into sodium heparin tubes on the day of enrolment (just before the first dose), 30 days after enrolment (1 month after the first dose) and 210 days after enrolment (1 month after the second dose).
Two plasma or sera samples were collected from each patient, one at day of enrolment and the second 7-14 dafterfeverfever onset.
Baseline serum creatinine concentration, measured on the day of enrolment, correlated well with serum creatinine concentration measured pre-enrolment, r = 0.72, P = 0.002.
Asymptomatic Plasmodium parasitaemia was defined by a positive malaria rapid diagnostic test result and/or by Plasmodium parasites detected microscopically plus the absence of unspecific symptoms of malaria at the day of enrolment or over the past seven days (i.e., fever, flue, cough, difficult breathing, and/or abdominal discomfort).
When his oldest sister, Gina, found out, she dragged him to a local sixth-form college on the day of enrolment, to retake his physics and art.
Physical and neurologic examination, electrocardiography (ECG), clinical-chemical and haematological screenings were done on the day of enrolment.
The fluid balance on the day before enrolment was almost 1 L higher in controls, possibly indicating a more aggressive initial volume replacement.
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