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On the TMZ-alone arm, patients received a starting dose of 200 mg m−2 per day, administered on days 1 5 of a 4-week cycle.
Mass antibiotic treatment was initiated approximately 48 h after the start of the investigation, with azithromycin, 250 mg orally each day, administered for 5 days to residents and to staff who wished to be treated at the facility.
Although the MTD of MSC with tested schedules in normal and tumour-bearing rats was 0.75 mg per rat per day (administered for up to 42 days), a single dose of 1.5 mg per rat was highly toxic.
To examine the correlation between plasma, CSF, and brain levels of AZD0530 in a preclinical model, five mice (C57B6/J) received a dose of 5 mg/kg per day administered orally twice daily for 3 days.
Patients received oral capecitabine 2000 mg m−2 per day administered in two divided doses for 14 consecutive days every 3 weeks.
During the treatment period, animals received an oral drench supplying 0 (control), 3 (Co3), 6 (Co6), and 9 (Co9) mg of Co/kg of BW per day, administered in 3 equal doses at 8-h intervals.
Similar(41)
In Thailand directly observed primaquine (1 mg/kg/day) administered over 7 days was well tolerated and reduced relapses by day 28 to 4%% [ 5].
The efficacy of a 3-day treatment regimen of Ampicillin-Sulbactam (AS 3 g × 3/day administered intravenously) is compared to a 3-day regimen of Ertapenem (1 g/day administered intravenously) for treating patients with localized peritonitis in a blinded evaluation of established efficacy-based endpoints.
The efficacy of a 3-day treatment regimen of Ampicillin-Sulbactam (AS 3 g × 3/day administered intravenously) was compared to a 3-day regimen of Ertapenem (1g/day administered intravenously) in the treatment of patients with localized peritonitis followed by blind evaluation of pre-established efficacy-based endpoints.
VNP40101M was tested against an in vivo panel of five pediatric brain tumor xenografts at a dose of 18 mg/kg/day administered for 5 days.
In a postischemic, denervated rat model, CsA (50 mg/kg/day) administered for 12-14 days resulted in significant nephrotoxicity with marked decreases in both glomerular filtration rate and renal blood flow.
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