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Index dates were defined as the first prescription/administration of a corticosteroid, immunosuppressant, or biologic between 2003 and 2009.
Patients' cohort entry dates were defined as the date of the first statin prescription after discharge from hospital.
For selecting controls, index dates were defined as the day on which an NSAID ulcer was diagnosed in each of the cases.
The four index dates were defined as follows: Index date 1: Time of first entry into the dialysis program for cases; time of personal interview for controls.
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For each case, the actual period of surveillance (or follow-up) is the interval between the entry date and the exit date, these dates being defined as follows: entry date is the later of diagnosis date and 1 January 1971.
Individuals with a prior index date were defined as previously diagnosed.
Patients with comorbidities of HTN, DM and Hch before the index date were defined as having metabolic syndrome.
Within that time-frame, patients who were received physical therapy within 14 days of the index date were defined as having received early physical therapy.
Those patients receiving physical therapy between 14 and 90 days from the index date were defined as receiving delayed physical therapy.
Usually, the event date is defined as t = 0.
The index date was defined as the date of the first triptan prescription.
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CEO of Professional Science Editing for Scientists @ prosciediting.com