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Data on admission dates, operation dates, discharge dates, and diagnoses were available in these registers.
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Due-dates, operation time and contracts between order and resource agents are considered as random variables.
Patients' characteristics were obtained from clinical and pathology records including gender, age, tumor location, histological grade, tumor stage, CEA level, preoperative laboratory data, operation date, operation method, tumor recurrence, follow-up date, and follow-up status.
The data include general information on the reactors namely, reactor type and containment type, design type, docket number, licensee, operating license issue date, commercial operation start date, renewed operation license issue date, and operating license expiration date.
Additional clinical data collected from these patients included age, gender, pathologic stage, histologic type, surgical treatment modalities, frequency of surgery, surgical methods, date of operation, date of initial diagnosis of lung cancer and date of discharge.
We extracted information about previous use of antibiotics, presence of a sinus tract, date of operation, operative side, and description of purulence in the operation notes.
More up-to-date operations tend to be run by older, traditional local families, many descendants of Greek immigrants who arrived in the early 1900s, and have huge landholdings.
Patients were followed from the date of diagnosis (either date of diagnostic staging or date of operation if staging date was not registered) in DGCD until date of death, emigration or end of follow-up.
Overall survival (OS; date of operation to date of death from any cause or last date of follow-up) and disease-free survival (DFS; date of operation to date of any sign of tumour relapse – local, regional or distant) were the primary endpoints.
Overall survival was defined as the time between date of operation and date of death.
Cancer-specific survival was calculated from the date of operation until date of death or last follow-up.
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