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An artificial start date was defined for 31 March 2008 to allow sufficient time for the application of prospective exclusion criteria, such as 'clinically significant gastrointestional bleeding within 6 months of randomisation'.
A follow-up end date was defined for each patient as the earliest occurrence of a diabetes endpoint, date of death, date of emigration, date of loss of continuous health or drug plan enrolment, 24 months after start of statin treatment, a dispensing for cerivastatin, or 31 March 2011.
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The controls were assigned the same date for start of follow-up as the matched case; this date was defined as diagnosis date for ovarian cancer plus 30 days, and defined as the index date.
For cases admitted to hospital, the index date was defined as the admission date for the first myocardial infarction or stroke.
Diarrhea onset date was defined as the start date for symptomatic infection.
The index date was defined as the first record for bariatric surgery.
For women in the comparison cohort, the index date was defined as the date of BC diagnosis for the matched case.
The index date was defined by the first pharmacy claim for basal insulin.
The index date was defined as date of suicide death for patients in the suicide death sample and also for patients in the control sample (who were alive on that date).
The index date was defined as the date of diagnosis for melanoma patients and as the date of the matched melanoma patient's diagnosis for members of the comparison cohort.
The index date was defined as the first admission date for a brain tumour, which was (later) confirmed to be a glioma by clinical pathology.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com