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The yield values were well correlated to the resistance measured by both incidence and by severity right from the second date of symptom observations, at the time of flowering.
METHODS: We reviewed medical and laboratory records to determine the date of symptom onset, the dates of hospitalization, and stool C. difficile toxin assay results for patients with CDAD who had diarrhea and positive toxin-assay results.
Hazard periods (person-time during which the event occurred) were defined according to date of symptom onset.
Knowing the date of symptom onset is a key to applying our proposed estimation framework to empirical observation.
The date of infection was estimated on the basis of one of the following: the date of symptom onset minus 15 days, the date of the incomplete Western Blot minus one month, or the mid-point between a negative and a positive ELISA test.
Date of symptom onset was not recorded for 32 patients.
When available, we used the date of symptom onset.
Date of symptom onset ranged from 17 March to 26 April 2013.
Of the 45 symptomatic lesions, exact date of symptom onset was available in 44 cases (97%%).
The questionnaire asked the date of symptom onset, symptoms, camp label, and hospital admission.
The date of symptom onset of cases was used as the index date.
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