Sentence examples for date of substantial from inspiring English sources

Nowhere are the challenges of preventing and treating paediatric infection more acute than in South Africa, home to more than one in seven of the world's HIV infected population [1], and where there is no evidence to date of substantial reductions in the prevalence of HIV in antenatal clinics [4].

To date there is no evidence of substantial decreases in C. finmarchicus abundance in the Gulf of Maine, but CPR data suggest a shift to greater numerical dominance of the small copepod group Para- and Pseudocalanus compared to Calanus finmarchicus, in the northwest Atlantic between the 1990s and the 1960s/1970s [1960s/1970s

Consistent with effective selection against higher mutation rates, there are no reports to date of mutator strains at substantial frequencies in natural yeast populations, despite the low rates of outcrossing inferred in such populations [ 43, 44].

To date, a substantial body of research has shown adverse health effects of short-term changes in levels of air pollution.

The Canadian Real Estate Association reported that the average price of existing homes rose 19.6 percent in January compared with those in the month a year earlier, the latest in a string of substantial gains dating back through last autumn.

To date, there has been no evidence of substantial tampering in the election.

To date, a substantial amount of research studies exist, which focus on activity recognition using inertial sensors.

To date, a substantial number of correspondence-testing studies, surveyed in Ahmed (2015), have convincingly shown that employers discriminate against job applicants by name.

To date, a substantial body of evidence has emerged to demonstrate that an individual's level of health literacy is associated with health-related outcomes [ 10].

To date, a substantial amount of work has focused on pathway analysis as a method to analyze and compare metagenomic populations (De Filippo et al., 2012).

Finally, as Chalmers has described, an up-to-date systematic review will also be of substantial value in two other important ways: to enhance interim results monitoring of an ongoing trial, and to facilitate the informative reporting of a trial's results in relation to existent knowledge.[ 13] The state of knowledge concerning treatment effects changes as evidence is cumulated and synthesized.