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Furthermore, the date of selection in Europeans was estimated to be around 10,000 years before present, suggesting that TRPV6 may have coevolved with lactose tolerance [13] as fresh milk is a major source of calcium in European populations.
This, and the proposed date of selection of about 10,000 years before present, led to the hypothesis that this locus may have co-evolved with lactase persistence with the onset of dairying in Europeans [1].
The reference date was the date of diagnosis for cases and the date of selection for controls.
The IBT and non-treated cohorts were both tracked from the date of selection until the end of 2009 or until loss to follow-up (i.e., withdrawing from the health insurance program) to identify new TB events.
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A total of 491 cases had mammograms within five years prior to and one year after diagnosis and 528 controls had screening or diagnostic mammograms close to the dates of selection into CBCS.
Study participants were asked about their lifestyle during the year, two years prior to the date of diagnosis or selection.
Knowledge of these loci provides some of the best examples to date of how human selection for certain physical traits in maize has led to specific changes at the DNA level.
To date, "Fst outliers" diagnostic of selection have been informative in several plant species, including sunflower [ 33], maize [ 16, 34], white spruce [ 26], and other conifers [ 35].
However, one of the limitations of Birth Date Selection Mapping is the requirement of a temporally stratified sample of genotyped individuals.
To date, the selection of the optimum joining technology in lightweight engineering is based on the expertise of the developer.
However, to date, the selection of image object sets to represent landscape patterns has been largely subjective.
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