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Epidemiological data including age, sex, and symptoms (diarrhoea and/or vomiting and their number of episodes), feeding type, date of onset, and date of sample collection were collected using Epic.
The line lists indicated the date of sample collection, but the type of sample collected (CSF and/or serum) and the laboratory test used (IgM ELISA, PCR, and/or cell culture) were not recorded for any of the case-patients.
Patient information including date of birth, date of sample collection and gender was routinely collected.
General patient demographic information was collected (date of birth, sex, date of sample collection, and invasiveness) for all case-patients.
Demographic and basic clinical information were collected from patients with carbapenem-resistant bacteria: age, gender, date of admission, clinical department, clinical diagnosis, origin of collected sample, isolated bacterial strains and date of sample collection.
"The player, who requested a personal hearing, will serve a 24-month suspension commencing 5 February 2013 (backdated to the date of sample collection) until 4 February 2015 [inclusive]." Kinsella, who was on Everton's books as a youngster, signed for Fleetwood last summer but has yet to make a first-team appearance.
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Overall, the mean (SD) number of days from onset of symptoms to collection of nasopharyngeal samples was 3.22 (1.5), and no correlation was found between initial nasopharyngeal viral load and time elapsed from symptom onset date to the day of sample collection (Spearman ρ –0.16, p = 0.156).
Although patient collection spanned 10 years, we carefully selected high-quality samples and controlled all experiments by grouping patients into a randomly selected discovery cohort and a validation cohort according to dates of sample collection.
Dates of sample collection and processing, time of day of blood collection, and time since last meal were recorded.
The resulting clusters are inspected manually for clustering of samples by non-biological parameters, such as the dates of sample collection and RNA extraction, the batch of in vitro transcription and amplification reagent used, and the date of array hybridization.
As the dates of sample collection for this study ranged from 1968 to 2009 and were run in random order over the 3 months, we estimated sample stability by arranging data for each ceramide species by date of study visit.
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