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23 Interestingly, despite that mutant S188T is located in antigenic site Sb and has become prevalent since 2009, 24 it appears to have had little impact in antigenic drift because no evidence has been reported to date of reduced vaccine efficacy caused by this mutant.
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In the limited examples (tb1 and tga1) examined in maize to date, the region of reduced polymorphism is short, presumably reflecting high effective rates of recombination as maize is an outcrossing species.
Keep your travel dates flexible to take advantage of reduced airfares.
Zidovudine (an NRTI) is the only drug to date for which there is evidence of reduced HIV transmission risk following occupational exposure.
We excluded patients who took drugs, including TZDs, that were prescribed during the 90 days preceding the index date to reduce the possibility of confounding due to indication.
The efforts made to date to reduce the emissions of arsenic and the measures planned for the next few years are described.
For this reason, we only included Parkinson's disease patients who did not have anti-Parkinson medication before the first diagnosis date to reduce the likelihood of including prevalent case subjects with a longer-term history of Parkinson's disease symptoms.
We also review the therapeutic strategies designed to date to reduce the detrimental effects of brain death in both marginal and optimal livers, attempting to explain why such strategies have not solved the clinical problem of liver transplantation.
The main pharmacokinetic interactions relevant to HIV management reported to date include reduced bioavailability of rilpivirine when coadministered with rifampicin, rifabutin or acid suppressing agents, and reduced bioavailability of ketoconazole.
The measures implemented to date have reduced the contribution of point sources of pollution, and hence diffuse pollution from agriculture has become more important.
Additionally, by excluding all patients with less than 3 years of active history prior to the index date, we reduced the risk of including prevalent rather than incident cancer cases.
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CEO of Professional Science Editing for Scientists @ prosciediting.com