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Cancer-specific survival was calculated from the date of primary surgical resection to the date of gastric cancer associated death or to the date of recorded cancer progression.
245 cases (71%) had at least one relevant investigation or a referral to a gynaecologist recorded in the 12 months up to and including the date of recorded diagnosis.
Outcomes of progressive disease were based on the well documented and validated Beneficiary and Identification Records Locator Subsystem files for occurrence of deaths that included date of recorded death, and Veteran Affairs nursing home files for date of being admitted to institutional care.
17 For each patient we also determined an exit date, which was the earliest of date of recorded fracture, date of death, date of deregistration with the practice, date of last upload of computerised data, or the study end date (30 June 2008).
The individual study cohorts for each cancer at time points 1, 2, 3 and 5 years from date of recorded diagnosis were compiled through the identification of the 312 cases diagnosed most closely to a specified time point (First of February for each year).
Observation time was calculated from the entry date to an exit date, which was defined as the earliest date of recorded fracture, date of death, date of deregistration with the practice, date of last upload of computerised data, or the study end date (30 June 2008).
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Mortality typically occurred in the postpartum period, beyond the standard date of recording maternal death.
We established gestational age as the computed interval between the date of last normal menses and the date of recording.
Third, we report the dates of recorded diagnoses.
Sixteen of these had a non-radical prostatectomy recorded in the APDC corresponding to the date of RP recorded in PCOS.
The date of death recorded was checked from the medical records or social security death index.
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