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Our study represents the largest study to date of outcomes due to SSI due to MRSA.
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In contrast, when the analysis was based on 26 weekly reports of exposure improperly completed on or after the date of outcome, the risk of recurrence associated with systemic infection was estimated to be 4-fold (rate ratio = 4.07, 95% CI: 1.84 8.98), and there was a suggestion of a 2-fold risk associated with high psychological stress (rate ratio = 2.02, 95% CI: 0.69 5.91).
Date of HAART initiation and date of outcome were used as the start and end point of follow-up time, respectively.
Controls were matched to cases on general practice clinic, sex, year of birth and date of outcome diagnosis in their matched case.
Each individual contributed person-time from study entry (for exposed: date of sex reassignment; for unexposed: date of sex reassignment of matched case) until date of outcome event, death, emigration, or end of study period (31 December 2003), whichever came first.
Follow-up time will be calculated for each participant from date of randomisation until the first among: date of outcome, date of death, or 22 October 2002 (when the trial was formally halted).
Person-years of observation (PYO) were calculated from the date of starting anti-TB treatment to date of outcome and was calculated as the number of deaths/100 PYO.
Post-operative survival was defined as the number of days between the date of the first curative resection and the date of outcome (death or censoring).
Post-operative survival was defined as the number of days between the date of the first colorectal resection and the date of outcome (death or censoring).
Postoperative survival was defined as the number of days between the date of the first resection and the date of outcome (all-cause death or censoring).
The data (Supplementary File S1) reported: date of disease onset; outcome (death/recovery); date of outcome; and likely source of transmission (syringe during outpatient visit/person-to-person transmission/both/other).
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