There is no clear evidence to date of its effectiveness as a cavity disinfectant, but it has been effective in vitro, combined with polyacrylic acid, in eliminating bacteria associated with residual caries [ 30].
Although comprehensive infection prevention and control programs have been recommended, there is little evidence to date of their effectiveness or of what aspects are most important.
Therefore, we will undertake a systematic review and meta-analysis of studies on fetal, infant and child-health outcomes related to the introduction of smoke-free legislation in order to obtain the most comprehensive assessment to date of its effectiveness in improving the health of babies and children worldwide.
To date the evidence of effectiveness for the management of fatigue using acupuncture is unclear.
While there has been a widespread introduction of the Nintendo Wii video games console and Wii Fit program there have been few clinical trials to date of it's effectiveness as a therapy tool when used with older people [ 11- 13].
There is insufficient evidence till date on the effectiveness of delivery of these services by ANMs; there is a need for well-functioning referral systems to be in place as a pre-condition as well as to validate clinical treatment algorithms used by ANMs in the delivery of these services [ 24].
Different economic and environmental theories and approaches have been used to date to evaluate effectiveness of biofuels policies, efficiency of biofuels production or sustainability of different biofuels technologies.
To date, the effectiveness of exercise recommendations for the prevention of weight regain has not been evaluated in a properly designed, adequately powered trial.
In one of the largest systematic reviews conducted to date on the effectiveness of chronic care models, Davy and colleagues [ 33] reported that no differences could be identified in health and practice outcomes between variant models.
To date the effectiveness of CDSS has been less than expected, especially concerning the ambulatory management of chronic diseases.
To date, the effectiveness of farm-based interventions for people with major depression was evaluated only by a limited number of studies.
