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The majority of the bacterial sRNA genes found to date is located in IgRs [ 3, 21] and the size of the sRNAs generally varies between 50 and 400 nt [ 1, 22].
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All of the SSLs described to date are located in mobile genetic elements [ 2].
Interestingly, in the mouse, all human PAR1 orthologs identified to date are located on autosomes.
TERT genes of the other amniotes analyzed to date are located on autosomes [ 43, 93].
Most cellular IRES elements characterized to date are located in 5' UTR and few of them are located in coding regions [ 36- 38].
The only QTL detected for flowering date was located on this linkage group and is associated with the upper stem characteristics of upper internode length and stem twining.
In contrast, the dominant mutations reported to date are located in the region that codes for the carboxyl terminus of AQP2 [ 55].
Most of the methylation marks characterized to date, are located in the N-terminal tails of the core histones H3 and H4.
The strongest signals discovered to date are located in the fat mass and obesity-associated (FTO) gene, which was originally found within a study on type 2 diabetes genes, but the association was mediated by BMI (6).
Inter-chromosomal translocations, structural reconstructions, and chromosome length variations are more likely to be observed at the end of telomere regions, where most of the cloned Avr genes to date are located [ 35].
All of the disease-causing ACTN4 mutations identified to date are located within the actin-binding domain of the encoded protein, increasing its binding affinity to F-actin and leading to abnormal actin rich cellular aggregates.
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