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It is not clear whether this is because of the type of data that is held in managed access datasets, which may not be suitable for a broad range of scientific uses, or whether it is because governance requirements are too restrictive.
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A neural network usually needs to be sufficiently trained by the full volume of dataset which may not be available in data streaming environment.
Users can also download the list of all occurrences of the motif module with their TFBSs under given conditions., The complete list of motif modules discovered for each motif in each dataset, which may not be validated by known interacting TF pairs, can be found in the download page.
Method 1 requires existing datasets containing EQ-5D in the patient population, which may not always be available.
There could be mutation targets common to these cancers which may not have been identified or is absent in the current dataset.
Alternatively, significant linkage may have been missed as a result of sub-optimal coverage of the genome by the STR marker set used, which may not have extracted all the inheritance information contained in the dataset.
Which may not count for much.
This is where a researcher who has collected information on a study cohort wishes to link this data to another dataset which may or may not already exist in the linkage system.
Interestingly, the five-miRNA panel indentified by Friedman et al. (2012) was not present in our dataset which may indicate that this panel is not specifically melanoma-related but instead related to the tumourigenic process.
They may reflect confounding by other covariates not shown in the public dataset, which may be correlated with the external dose used here (and in LSS12) and may also interact with radiation and may vary over time.
Local models are based on chemical similarity amongst the dataset which may be structural or mechanistic.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com