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Pappilary thyroid carcinoma and breast cancer datasets were retrieved from the GEO database [23], accession GSE3467, GSE3744, and ArrayExpress database [24], accession E-MEXP-882.
Biochemistry datasets were retrieved for 407 patients.
SAGE datasets were retrieved from GermSAGE (http://germsage.nichd.nih.gov/germsage/home.html).html
A total of 1092 microarray datasets were retrieved.
Two datasets were retrieved from the Nucleotide Archive (http://www.ebi.ac.uk/ena/).ac.uk/ena/
Normalized datasets were retrieved from the Cancer Genome Atlas (TCGA) data portal (http://tcga-data.nci.nih.gov/).
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Expression data of S100 genes in microarray datasets was retrieved and the differences in expression levels between normal and gastric cancer tissues were determined by student T test.
In spite of this, no significant matches to additional miRNA families, apart from those present in the Vvi dataset, were retrieved.
mRNA decay rates of the genes in our dataset were retrieved from the report/analysis of Yang et al [ 45] where they measured the mRNA decay rates of 5,245 human transcript.
The 19 X-ray structures of the Fold-X dataset were retrieved from the Protein Data-bank (PDB 4) for comparative analysis with AutoDock vina. 10 AutoDock vina version 1.0.3 for Linux was downloaded as executable from the website of its authors.
A first dataset was retrieved from the Directorate General Statistics and Economic Information DGSEII).
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