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To check whether the alignment process itself makes a difference, two additional datasets were made by recovering the sequences from the simulated alignment and aligning them using the same procedure as for the biological sequences.
These different coverage datasets were made by first extracting all mouse specific reads from SOD1-G93A entire mate-pair library and then extracting reads from mouse specific fastq files by seqtk package (sample utility at different seed values).
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The fusion of the gravity datasets is made by the band-limited least-squares collocation, which best integrates datasets of different accuracies and spatial resolutions.
The management of a dataset is made by a database management system (DBMS).
A specific nucleotide dataset was made by exclusion of the third nucleotide codon positions.
A reconstituted dataset was made by pasting the consensus for every allele the number of times it was observed in the sample, according to Timmmermans et al., in press These datasets were aligned with each other and an alignment with the out-group Orchesella villosa pmt sequence was provided.
The datasets were made anonymous and prepared by the government sector for public use.
Comparisons between microarray datasets were made using Microsoft Excel and Access.
As in the risk sharing cohort, in the Ontario dataset diagnoses were made by experienced neurologists according to standard clinical criteria.
The Amazon, CoRA, IMDb, PubMed, Wikipedia and Youtube datasets are made available by Nandanwar and Murty [1].
2D Tanimoto similarity searching of these datasets is made available by the gNova CHORD tanimoto function applied to the 2D public 166 keys, an implementation of the popular MACCS keys.
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