A separate analysis, where we identified clusters of genes that were co-regulated within the datasets, showed a large degree of overlap.
The dataset shows a large range of UCS (as observed for the other physical properties), from 60 to 211 MPa.
Overall, kinases in the dataset showed a large variation in their associated number of inhibitors: 76% of kinases were inhibited by 10 to 70 compounds, only a single kinase (NEK7) was not inhibited by any compound, and the remaining kinases were inhibited by 71 or more compounds (for a visualization see Figure 2).
Compared with the NCBI reference list of human genome, this dataset showed a larger proportion of genes encoding proteins involved in chromatin binding and architecture, organelle organization, intracellular transport and neurotransmitter secretion (Table 3).
Compared with the NCBI reference list of human genome, this dataset showed a larger proportion of genes encoding nucleic acid binding proteins, such as histones and ribosomal proteins and genes involved in chromosome segregation and mRNA transcription (Table 3), possibly suggesting the induction by HCV of specific new pathways.
Other studies on larger datasets show a correlation that is high but nevertheless significantly different from 1 [ 45, 46] which implies that maternally, the gestation length of a heifer and a cow are genetically distinct traits.
Based on our small dataset, we could show a large discrepancy between visual and quantitative analysis, yielding inconsistent results in up to 42.3%% of the inspected lesions.
In the automatic personality recognition research literature, the datasets and features pointing at personalities show a large amount of diversity in terms of their data domains.
In contrast, large nuclear protein datasets of mammals with diverse taxon sampling [e.g.3], [4] show a large proportion of missing data.
In general, earlier studies overestimated variances between species [ 35], while more recent studies using larger and more standardized datasets showed a much higher level of conservation [ 6].
