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Therefore, we conclude that our datasets have been validated by both general and targeted studies looking at abundance changes in replicatively aging yeast.
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The issues have affected the accuracy of a small number of individual prescription records within the IPCRN dataset that have been validated against the GP's own records.
These patterns have been validated in independent datasets representing different laboratories, platforms and different patient cohorts [ 2].
Here we present an integrative analysis of high-throughput genomic and transcriptomic data; the resulting multi-omic signatures of therapeutic drug response have been validated across independent datasets.
Furthermore, these links have been validated through this datasets use in a large number of research projects and published research articles [ 1].
Whilst some biomarkers correlate with melanoma progression and survival, few have shown significance independent of other well known and more easily measured prognostic parameters (such as tumor thickness) and even less have been validated in independent datasets [ 8– 20].
The final set of CNVs detected in this study using this pipeline have been validated in multiple datasets, comparing common samples on MetaboChip, comparing CNVs to the DGV, examining transmission rates in trio data and by qPCR replication of specific loci.
It consists in withdrawing all the variants occurring only once in the dataset, which considering our criteria would not have been validated at the end of the process in any case.
Our results were checked against selected high-resolution structures from an external dataset, for which the positions of the hydrogen atoms have been validated manually.
Predictions from the layered shell model have been validated using several out-of-plane experimental datasets reported in the literature.
The predictions of the layered shell model have been validated using several out-of-plane experimental datasets reported in the literature.
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