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The two available worm 3'UTRome datasets estimate that approximately 46% of C. elegans genes use APA [ 5, 6].
Monte Carlo simulations are carried out to replicate datasets, estimate prediction model parameters and validate them using Lin's concordance measure.
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We generated reasonably noisy datasets, estimated the parameters using different methods, ordered the model coefficients according to their estimated values and assessed the ROC AUC score of such ordering.
When only the two oldest age classes were considered, 61 simulated datasets estimated N e > 1000.
Both datasets estimated gestation age based on last menstrual period, but it is likely that the larger numbers in the U.S. dataset improved precision.
One dataset estimates ETa based on the Simplified Surface Energy Balance (SSEBop) model while the other one estimates ETa based on the Atmosphere-Land Exchange Inverse (ALEXI) model.
It may be noted that the distribution pattern of observed dataset was found to be same as the distribution pattern of dataset estimated by the GGIUH model for five events (Table 8).
For carbon sequestration, again, estimates were only made for wooded land cover categories for those areas inside the range of our dataset estimates derived from the correlation equations were used.
The false discovery rate for this dataset, estimated at <1%, was calculated by dividing the sequence-reversed proteins that failed to be eliminated after applying the above criteria.
These used the maximum clade credibility chronogram from the combined dataset estimated in BEAST.
Bayesian relaxed clock dating using the combined dataset estimated the split at approximately 17.25 ± 0.36 Mya ± SE.
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