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Fasta-formatted sequence files were aligned using MUSCLE, with aligned datasets converted to Nexus format using the program seqConverter.pl, version 1.1 [187].
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It can be a time-consuming operation on large datasets, converting in the order of 40 000 sequences per second, although this is only around 70% slower than converting SAM to BAM using SAMtools.
Concatenated maximum likelihood phylogeny inferred using RAxML, from the full 29 species, 107 locus dataset, converted to amino acid sequences, under the Dayhoff substitution model.
The key algorithmic idea of the QUBIC program is based on the graph representation of a microarray dataset, converting the bi-clustering problem into a graph problem [ 21].
Part 1 of the web appendix describes the methods used to recover the original SDHS dataset; convert these data into a useable format; and identify, confirm, and verify the recovered data.
Use Case II: The DataTank: Once the data of the four pilots was identified and catalogued in Micka or CKAN, it was necessary that some datasets were converted in different formats, as not all identified datasets were geospatial ones.
So that annotation information was consistent between all datasets, the positional information for all the genotype datasets was converted to build 36 of the Human genome using the UCSC liftover tool when necessary [ 41].
As highly imbalanced problems, the satimage dataset and yeast dataset were converted into binary class problem: the class "damp grey soil" and the other classes in satimage, and the class "ME2" and the other classes in yeast.
After the data-scrubbing and preprocessing, the datasets were converted into a form suitable for database processing, operations and fusion.
These datasets are converted into a data array (similarly to the method explained above).
All datasets were converted to the BDGP5 Drosophila genome annotation as needed.
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