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Building and evaluating classifiers based on these synthetic datasets can be problematic, as it has been observed that they are not necessarily representative of real world review spam.
Rigorously assessing patterns of congruence and conflict between datasets can be problematic in and of itself [131].
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For intermediate to large datasets, the calculation of BrS can be problematic, because support values can turn out to be severe overestimations of support [ 35] unless relatively thorough search strategies are invoked to assess support of each branch.
However, with the increasing availability of whole-genome datasets, such a restriction on the reconciliation model can be problematic as losses are a rich source of information that can be critical for accurate reconciliation.
This requires users to upload their data to the MG-RAST servers, which can be problematic and slow for large datasets.
The results can be problematic.
Lifting an object can be problematic.
Even genuine documents can be problematic.
Displaying insects can be problematic.
This kind of spending can be problematic.
"Magic Kingdom can be problematic," he said.
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