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However, overall differences between our three attribute datasets are minimal (averaged r2 values: TSM, 0.71; All, 0.70; and IAS, 0.68).
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Incomplete datasets were minimal.
Reassuringly, differences between datasets were minimal at a regional level, but at higher data resolutions (postcode areas) meaningful and potentially concerning differences were detected.
The degree of preconditioning in our dataset is minimal, such that there is allowance in the data for disagreement with the consensus dinucleotide introns sequences, gt and ag, as well as the incorporation of reverse encodings.
Using the INDEPTH 2013 standard, encompassing lower income populations in both Africa and Asia, meant that the overall effect of standardisation across the whole mortality dataset was minimal, while resulting in important adjustments for certain sub-groups.
2, 4 However, complete-PBPK models rely heavily on knowledge of tissue concentrations, and as such application to clinical datasets has been minimal, raising doubts as to their necessity in most cases.
There are minimal differences in imputation quality when comparing the 2,972,940 SNPs common across the two datasets [mean Rsq, 0.886 (median = 0.972, IQR = 0.123) for the HapMap imputed dataset against 0.903 (median = 0.978, IQR = 0.097) in the 1KG imputed dataset].
Celebrity appearances are minimal.
Slips are minimal.
Overheads are minimal.
Current protections are minimal.
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