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The estimated regression coefficient of each PFS-related gene given by ridge regression in the discovery set was also applied to calculate a prognostic index for each patient in external dataset using the equation above.
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The cutoff Θ that maximizes the Youden's statistic was estimated on the development dataset using the following equation: Θ = arg max (Sensitivity + Specificity -1).
In addition, we estimated plot biomass using moist forest tree allometry [86] based on measurements of DBH from our tree inventory plots, WSG (as described above) and height data (derived from our dataset using the best fit DBH-height equation form [Equation 5.1; see Additional file 1: Sif], if not measured in the tree inventory plots).
In addition, we estimated plot biomass using moist forest tree allometry [ 86] based on measurements of DBH from our tree inventory plots, WSG (as described above) and height data (derived from our dataset using the best fit DBH-height equation form [Equation 5.1; see Additional file 1: Sif], if not measured in the tree inventory plots).
Let I K be the identity matrix of size K× K, we write (18) given the TG of a dataset, using the transition matrix M defined in Equation (7) and the preferential probability matrix H defined in Equation (18), we can perform PRW on the TG.
Full dataset accuracies were computed using the equation where k is the classification cutpoint [ 13].
MBL was calculated using the equation (1).
The formula is defined as: (4) The reference threshold was calculated from the verifying dataset using equation (2) to determine the number of clusters.
In each simulated dataset, the benefit of treatment on the outcome was first estimated by fitting a logistic model applied to the PS-matched dataset using generalized estimating equations with robust variance estimator (package gee for R, Vincent J Carey, Thomas Lumley and Brian Ripley).
Use the equation.
Use the equation t = 70/k.
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