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The nearest neighbor search problem is formulated as a dataset preprocessing that allows nearest neighbors queries to be answered efficiently.
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Using a lung cancer microarray dataset (Stearman et al., 2005), we compared the lists of DV genes discovered from the dataset preprocessed by five procedures.
The VMPFC subset of the spider monkey dataset was downloaded from http://www.pritzkerneuropsych.org/?page_id=400 (the RMA dataset preprocessed by the authors).
For example, if we identified 100 DV genes in a dataset preprocessed by DFW, we can estimate that about 65% of these genes would also be found if the data were preprocessed by RMA or FARMS.
RNA-Seq dataset and preprocessing (Dataset I).
Importantly, we noted that signal detection slope compression also varies by dataset, indicating that effect sizes measured by log-fold changes are not necessarily comparable between datasets preprocessed separately.
Surprisingly, the number of peptide matches is slightly higher for s = 100% (all peaks are included in the sequence ladder search) than for the datasets without preprocessing.
For example, we observed by exhaustive search that there are as many as 10,173 perfect 3-gene subsets for classification with the weighted voting method proposed by Golub et al and with their proposed training-test split [ 1]; and these gene subsets cover 3,337 genes (93.4% of all the 3,571 genes in the datasets after preprocessing).
Lin Zhu collected the experimental datasets and preprocessed the datasets.
The raw dataset was preprocessed before the fraud detection process begins.
In the first part, the Chemical Space Mapping, the molecules in the dataset are preprocessed.
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