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This choice of training dataset is reasonable because the Fantom3 dataset is highly heterogenous (broad length distribution, multiple experimental data sources (Carninci et al. 2005)) and the computational datasets represent whole genome scans.
So far, the clinical validation of FFR-CT opens the issue if the use of this software integrated to CCT dataset is reasonable in terms of cost-effectiveness in intermediate risk patients by "one-stop shop" offering coronary anatomy and functional relevance of CAD.
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This was consistent with the results of accuracy, precision, and dissimilarity, which to some extent demonstrated that results based on our simulated datasets were reasonable and consistent.
The partitioning for this dataset is quite reasonable except occurrence ovary tissues in different partitions.
While these are important considerations for higher resolution analysis of a gene family, use of simple statistical analysis for such a large and diverse dataset is a reasonable approach to defining areas of conservation or change, accepting internal error for random mutation producing homoplasy or loss of an actual synapomorphy.
The extent of overlap between the two datasets was low, so it is reasonable to say that the results derived from one dataset can complement those derived from the other.
In order to calculate the number of FPs per dataset, it's reasonable to assume that there were 26 datasets in the testing set.
However, our more general algorithms appear to work well with the Rosa datasets, for which the assumption is reasonable.
Because this simulation is based on our human microsatellite dataset, its results suggest that it is reasonable to make interpretations about allelic distributions in human populations using our method applied to the data in our example.
Considering that the biopsy tissues for the datasets contain immune cells, inflammatory response is reasonable for functional enrichment.
We believed it is reasonable to eliminate these two subjects from the dataset.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com