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The comparison between the deterministically derived synthetic dataset (equivalent to 5175 years) and the historical dataset (=161 years) showed that the surge level for the longer synthetic dataset was much higher at various return periods than the historical dataset.
In the work of del Amo et al. [45] a larger subset of Obach et al.'s dataset was used, containing 642 drugs – even larger than our Vss-target dataset, since they did not need to remove compounds occurring in a separate Kt:p-target dataset (they do not use any dataset equivalent to that).
The first algorithm (algorithm 1) was based on data (i.e., truncated dataset) equivalent to information found on the death certificate: demographic variables (e.g., age, sex, and race); cause and manner of death; plus a brief description of the circumstances of death (i.e., a short narrative reported by the death scene investigator).
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The power to detect an effect in the smaller Caucasian non-endometrioid tumor and Asian SECGS datasets, equivalent to that seen for the best SNP (rs11263763) in the main analysis including the four Caucasian datasets for all histologies, was calculated using QUANTO 1.1 (47).
For the heart, the model's performance on both dataset is equivalent to within 1 standard deviation for both AUCLMH_All and AUCLMH_TV.
For the miRNA-mRNA negative correlations, a p-value of 10-4 was used, which, in our dataset, was equivalent to an FDR of 0.05 on the genome-wide scale.
This dataset is not entirely equivalent to a dataset of low resolution structures with only Cα positions available as the accuracy associated with Cα positions in the dataset of Cα-only structures is expected to be higher (owing to the higher resolution) than that of true low-resolution structures.
The sensitivity of the algorithm varied depending on whether it was applied to dictated autopsy records, including all pathologic diagnoses, or to a truncated dataset containing records equivalent to that found on a death certificate (i.e., basic demographic information and causes of death).
For analysis of the whole datasets, Hamming distances (equivalent to p-distance) were used because some of the families were so diverse that using a substitution model was not possible.
This condition is sufficient to ensure that, for our chosen imaging modality, our synchronization scheme is able to acquire a 3D dataset with positional resolution equivalent to that which would be achieved were the heart hypothetically to be "frozen in time" for scanned 3D imaging.
For these results, we considered only the top five weighted TF IDF words for each article in the evaluation dataset, as this is the equivalent to the results of the training dataset.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com