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The distribution of seismic facies identified in the dataset, coupled to geomorphic trends and published sea level curves, allowed us to reconstruct the LGM to postglacial depositional history of these deposits.
Further, continued mining of the proteomic dataset coupled with analysis of novel factors in physiologically relevant models will continue to yield fruitful avenues for investigation into the biology of cardiovascular development and pathogenic mechanisms of CHDs in the hope of advancing prevention, diagnosis and treatment.
The retrieval of all fragments for each gene with no false positives from the artificial dataset, coupled with the lack of correlation between 33 of 35 single copy marker gene abundance, and estimated phosphate concentration in GOS samples suggests that IHAT worked equally well on highly conserved and less conserved genes.
The comprehensive nature of the dataset coupled with the ability to utilise the Primary Care Mortality Database has allowed us to assess the relative impact of these factors on survival.
This large dataset coupled with the availability of clinical data for cases related to Singapore patients and our molecular observations during in vitro cell passage presents an opportunity for a comprehensive analysis of the SARS-CoV mutational behavior.
A large and uniquely detailed dataset coupled with a novel Bayesian modelling framework that allowed for simultaneous quantification of the mean shift in Hb associated with each risk factor, and subnational risk of anaemia in school-aged children attributable to risk factors.
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Recent progress in molecular psychiatry and the use of multiscale datasets coupled with machine learning techniques may help to refine predictive models of conversion to bipolar disorder in clinical and population samples (Kapczinski and Passos 2015).
Joinmap software calculates consensus map by a regression algorithm only, while Carthagene allows one to work with the maximum likelihood even for integrated datasets, coupled with effective marker order refining procedures.
However, the complexity of biological systems and omics datasets require an integrative analytical environment, which allows network manipulation at different levels of detail, flexible mappings between multiple omics datasets coupled with data visualization and providing statistical analysis and system simulation and visualization of resulting analysis.
In particular, pTRACA22 appeared well represented in the combined human gut metagenomes analysed, and the absence of nucleotide sequences homologous to this plasmid in the non-human datasets, coupled with its presence in human gut datasets from geographically isolated individuals with a broad global distribution, suggests that pTRACA22 may be unique to the human gut microbiota.
In our previous study, 16 we presented a data integration approach in order to detect protein protein interactions across human host and P. falciparum, where information from experimentally identified protein protein interaction datasets coupled with expression and subcellular localization data aided the identification of feasible host parasite interactions.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com