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The usefulness of the proposed estimation and hypothesis testing procedures is illustrated by means of a small simulation study and a real-life dataset arising from physiology.
Original miRNA expression dataset and the reconstructed miRNA expression dataset arising from PCA were used to implement this process, respectively.
For the reconstructed miRNA expression dataset arising from PCA, we still adopted the same mutual information estimation method to construct miRNAs interaction network.
Missing values in the dataset arising from item non-response have been imputed to avoid bias generated by listwise deletion of subjects with missing values from statistical analyses.
The cumulative probability distributions comprise all measurements from five independent replications of every set of hemichannel variants that is the entire dataset arising from the image analysis of these connexin variants.
In addition to issues mentioned by the reviewer, we note that there may exist more problems such as the generic variations within the same dataset arising from the difference in physical/chemical properties of the peptides.
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> -wrap-foot> The observations above raise the question of where the correlations on the full dataset arise from.
The need to compare compound datasets arises from various scenarios, like mergers, library extension programs, gap analysis, combinatorial library design, or estimation of QSAR model applicability domains.
The choice of testing the Similarity Index on these two datasets arises from the goal of finding a setting for the SI that potentially could give good performances on different kinds of data, thus implementing a "generic" idea of chemical similarity.
We believe that Beagle's difficulties in imputing African datasets arise from properties of its clustering model.
The similarity between these covariance vectors and the first PC loadings confirm that the greatest source of variation in both datasets arises from the difference between the two species.
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CEO of Professional Science Editing for Scientists @ prosciediting.com