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> -wrap-foot> The observations above raise the question of where the correlations on the full dataset arise from.
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The usefulness of the proposed estimation and hypothesis testing procedures is illustrated by means of a small simulation study and a real-life dataset arising from physiology.
Original miRNA expression dataset and the reconstructed miRNA expression dataset arising from PCA were used to implement this process, respectively.
For the reconstructed miRNA expression dataset arising from PCA, we still adopted the same mutual information estimation method to construct miRNAs interaction network.
Missing values in the dataset arising from item non-response have been imputed to avoid bias generated by listwise deletion of subjects with missing values from statistical analyses.
The cumulative probability distributions comprise all measurements from five independent replications of every set of hemichannel variants that is the entire dataset arising from the image analysis of these connexin variants.
In addition to issues mentioned by the reviewer, we note that there may exist more problems such as the generic variations within the same dataset arising from the difference in physical/chemical properties of the peptides.
Missing values in the dataset arising from item non-response have been imputed in order to avoid any bias generated by listwise deletion subjects with missing values from the statistical analyses using the procedure hot deck imputation.
Massive datasets arise in a broad spectrum of scientific, engineering and commercial applications.
Such datasets arise in many areas computational simulations, observation networks, medical imaging, and 2-D and 3-D rendering.
However, several concerns linked to the use of any kind of anatomical information for PVC on cardiac datasets arise.
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