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Contributors that were not active before the last month in the dataset are excluded due to the small amount of information available about their behavior.
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In all experiments, subjects who quit early or otherwise failed to submit a complete dataset were excluded from further analysis, as were subjects whose median response time across all trials was less than 1000 ms, which suggested that they simply clicked through the experiment without actively participating.
The other complexes of the Astex diverse dataset were excluded as either no other complex structures of the respective protein (at 100% sequence similarity) were available or the available structures contained ligands whose structural features and/or binding mode differed massively from that of the query ligand.
As a result of applying these stringent criteria 41% of the total sequences in the 27F data set, 37% of 534R dataset and 22% of the 27F-534R dataset were excluded from the analysis.
For this purpose, KO selected a large sample of the original all-occurrence database of the habituated males (N = 877 calls, the remaining 17.8% of the entire dataset were excluded because of substandard recording quality).
Proteins that share >30% sequence identity with proteins from the original Höglund dataset were excluded.
The IEEE (Spain) dataset was excluded from the analysis for other reasons (see below).
This finding resulted in no distinguishable categories, and therefore this dataset was excluded from further calculations.
The latter dataset was excluded from our analysis because it did not contain any AD data.
The bird dataset was excluded for better visualisation because it was independent from the other datasets (see Table 5).
The results were analyzed exhaustively and any extracellular location associated domain containing protein sequence in the negative dataset was excluded.
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CEO of Professional Science Editing for Scientists @ prosciediting.com