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In particular in clinical applications, MALDI biotyping is thus widely used and comprehensive databases of reference spectra exist for medically relevant microorganisms.
For clinically relevant microorganisms, comprehensive databases of reference spectra exist, but organisms from agricultural ecosystems are often not included in commercially available databases.
Large databases of reference sequences, such as Greengenes [ 9], SILVA [ 10] and RDP [ 11] already exist for metagenomic sequence analysis.
When aligned to these large databases of reference potential poxvirus amplicons (using BLASR), the correct strain, vaccinia-Lister, is identified as the poxvirus with the largest number of bases aligned from the query dataset.
Currently, the most convenient tools to reconstruct metabolic networks from genome annotation are databases of reference pathways such as BioCyc (Karp et al., 2005) and KEGG (Kanehisa et al., 2008).
Furthermore, identification of microorganisms by MS has started to become a commonplace method, which is reflected by diverse companies providing dedicated hard- and software solutions as well as comprehensive databases of reference spectra for robust, automated data recording and analysis [ 8, 9].
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The Stinsons' eventual goal is to build a DNA database of reference samples, so that all manuscripts can be dated and located.
Meanwhile, New York State authorities are collecting a database of reference samples from relatives of the victims, as well as a database of samples taken from the victims' personal effects (toothbrushes, combs, etc).
When netLibrary opened in March 1999, for example, it was promoted in press releases as a company that would "revolutionize the library system" by enabling people to tap into a searchable and comprehensible database of reference and scholarly books.
A database of reference images with known surface roughness values was established.
This would also lay down a path for future researchers and create a database of reference in the Indian context.
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