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The reason is related to the complexity of the databases incorporating more or less artifacts.
In this direction, the release of databases incorporating atomic mapping of metabolites at large scale is promising [ 57].
Over time, as sequence databases, incorporating data from larger numbers of patients and healthy individuals, become available to clinicians, the power of this approach is likely to increase.
With the explosively growing data scale, the development of biological databases incorporating different species has become a very important theme in big data biology.
Actually there exist well-known ortholog databases incorporating GO terms to illustrate functional evolution, such as Roundup (9) and YOGY (14).
The reviewer makes an excellent point that customized databases incorporating ribosome profiling data for proteomic searches are likely to have a significant impact on future studies.
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Over 300 manuscripts use CTD data, and more than 30 public databases incorporate CTD data.
These databases incorporate over 60,000 sequenced exomes with partly overlapping content.
The experiments from these databases incorporate a wide variety of mutants, environmental conditions and stages of development.
The databases incorporate four types of data: a complete polymorphism catalogue, genotype data from specific projects, phenotype data and selected resequencing data.
Those databases incorporate not only information on histones and histone-modifying enzymes but also include other proteins affecting the chromatin structure without direct histone modifications.
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