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Firstly, the titles and abstracts of the citations in the Reference manager database will be assessed by one reviewer.
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Two independent investigators will enter the data in a centralized database; data quality will be assessed.
Any changes or updates suggested by external users will be assessed by the database manager before being entered into the database.
Firstly, titles and/or abstracts of all citations in the master database (that is, irrespective of test type) will be assessed by one reviewer.
Health care resource utilization and costs (baseline and 6 months): Health care resource utilization will be assessed through financial micro-costing databases.
The outcomes of the intervention will be assessed by linking the claims management database to the VSTR and VOTOR.
For RCTs, methodological quality will be assessed against the 11-item Physiotherapy Evidence Database (PEDro) scale.
Incident CVD outcomes will be assessed through linkage to administrative healthcare databases (619 886 person-years of follow-up until 31 December 2011).
In addition, asthma-related health care utilization (HCU) will be assessed through data extraction from KPNC electronic databases for the period of 12 months pre- and post-randomization.
Baseline measures and outcome data (during a three year follow-up) will be assessed through clinical examination, patient questionnaires and NHS databases.
The abstracts of articles identified through searching other resources will be assessed using the same criteria as for studies identified through electronic database searches.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com