In addition, data from 183 breast tissues in the GTEx (V6) (2015) publically available online databases were evaluated to obtain information on whether the most interesting variants (rs1905339, rs8074296, rs146170568, chr17:40607850:I and rs77942990) were expression quantitative trait loci (eQTL) for any gene.
Firstly, all identified studies were imported electronically into EndNote® bibliographic database (Thomson Reuters, New York, NY, USA) and were evaluated on the basis of titles and/or abstracts against the prespecified eligibility criteria.
These results for degraded and mismatched conditions were evaluated on the female speaker database solely as no degraded version of the male database was available.
For evaluation purposes, we designed a so-called GOA benchmark of 1000 MEDLINE abstracts sampled from the curated section of the GOA database, and our two local GO classifiers were evaluated on their ability to extract the GO terms that were manually associated with these abstracts in the curated subset of GOA.
Mispredictions were evaluated on four distinct databases not expected to contain polyadenylation sites (Table 2), the size of which was adjusted so that the number of false sites (TN+FP) was the same as the number of true sites (TP+FN).
The segmentation systems were evaluated on different broadcast news databases.
PubMed, Cochrane, and Embase databases were evaluated through September 31 , 2016
All databases were evaluated by two authors in November 2005.
In the second part of the experiment, classifiers were trained and tested on the test database only, using 10-fold cross-validation in which each classifier was trained on 9/10 of the test database, and its precision was evaluated on the remaining 1/10.
This approach contrasts with what might be called battery gene set testing, in which a large database of gene sets is evaluated on a microarray dataset, to see whether any sets stand out from the others (Dørum et al., 2009; Efron and Tibshirani, 2007; Saxena et al., 2006).
